SQLite

PEAR :: Package :: DB_Sqlite_Tools
An object oriented PHP interface to manage and backup Sqlite databases.
http://pear.php.net/package/DB_Sqlite_Tools

Pysqlite
A Python interface using the SQLite embedded relational database engine that conforms to the Python Database API Specification 2.0. [Open Source, zlib/libpng license]
http://oss.itsystementwicklung.de/trac/pysqlite/wiki/WikiStart

SQLiteDB
Simple PHP SQLite class written in PHP for enabling SQLite database management directly from within PHP scripts [Open Source, GPL].
http://code.jenseng.com/db/

System.Data.SQLite
ADO.NET 2.0 Provider with VS 2005 design-time support. Available for standard and Compact Framework. Downloads and a forum are available.
http://sqlite.phxsoftware.com/