Object-Oriented

Vortex
Language-independent optimizing compiler infrastructure for OO and other high-level languages, coded in Cecil, whole-program optimizer with aggressive analyses and optimizations. Front-ends: Cecil, Smalltalk; C++, Java; Modula-3. Outputs portable C++, SPARC assembly.
http://www.cs.washington.edu/research/projects/cecil/www/vortex.html